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Negative in vitro selection identifies the rRNA recognition motif for ErmE methyltransferase.

Erm methyltransferases modify bacterial 23S ribosomal RNA at adenosine 2058 (A2058, Escherichia coli numbering) conferring resistance to macrolide, lincosamide, and streptogramin B (MLS) antibiotics. The motif that is recognized by Erm methyltransferases is contained within helix 73 of 23S rRNA and...

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Bibliografische gegevens
Hoofdauteurs: Nielsen, A K, Douthwaite, S, Vester, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369827/
https://ncbi.nlm.nih.gov/pubmed/10445878
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