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Modification of Asn374 of nsP1 Suppresses a Sindbis Virus nsP4 Minus-Strand Polymerase Mutant

Our recent study (C. L. Fata, S. G. Sawicki, and D. L. Sawicki, J. Virol. 76:8632-8640, 2002) found minus-strand synthesis to be temperature sensitive in vertebrate and invertebrate cells when the Arg183 residue of the Sindbis virus nsP4 polymerase was changed to Ser, Ala, or Lys. Here we report the...

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Detalles Bibliográficos
Main Authors: Fata, Cori L., Sawicki, Stanley G., Sawicki, Dorothea L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC136982/
https://ncbi.nlm.nih.gov/pubmed/12163583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.17.8641-8649.2002
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