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Molecular dynamics studies of U1A-RNA complexes.

The U1A protein binds to a hairpin RNA and an internal-loop RNA with picomolar affinities. To probe the molecular basis of U1A binding, we performed state-of-the-art nanosecond molecular dynamics simulations on both complexes. The good agreement with experimental structures supports the protocols us...

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Bibliografiska uppgifter
Huvudupphovsmän: Reyes, C M, Kollman, P A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1999
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369755/
https://ncbi.nlm.nih.gov/pubmed/10024175
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