Genetically Stable Picornavirus Expression Vectors with Recombinant Internal Ribosomal Entry Sites

In many respects, picornaviruses are well suited for their proposed use as immunization vectors. However, their inherent genetic instability hinders application for prophylactic purposes. We demonstrate the improved expression and stability of a heterologous insert through a novel vector design stra...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dufresne, Andrew T., Dobrikova, Elena Y., Schmidt, Stacie, Gromeier, Matthias
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12163617/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.17.8966-8972.2002
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