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Genetically Stable Picornavirus Expression Vectors with Recombinant Internal Ribosomal Entry Sites

In many respects, picornaviruses are well suited for their proposed use as immunization vectors. However, their inherent genetic instability hinders application for prophylactic purposes. We demonstrate the improved expression and stability of a heterologous insert through a novel vector design stra...

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Библиографические подробности
Главные авторы: Dufresne, Andrew T., Dobrikova, Elena Y., Schmidt, Stacie, Gromeier, Matthias
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC136971/
https://ncbi.nlm.nih.gov/pubmed/12163617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.17.8966-8972.2002
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