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Genetically Stable Picornavirus Expression Vectors with Recombinant Internal Ribosomal Entry Sites
In many respects, picornaviruses are well suited for their proposed use as immunization vectors. However, their inherent genetic instability hinders application for prophylactic purposes. We demonstrate the improved expression and stability of a heterologous insert through a novel vector design stra...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136971/ https://ncbi.nlm.nih.gov/pubmed/12163617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.17.8966-8972.2002 |
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