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Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain
PEA-15 is a multifunctional protein that modulates signaling pathways which control cell proliferation and cell death. In particular, PEA-15 regulates the actions of the ERK MAP kinase cascade by binding to ERK and altering its subcellular localization. The three-dimensional structure of PEA-15 has...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136945/ https://ncbi.nlm.nih.gov/pubmed/12456656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf641 |
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