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High-throughput trapping of secretory pathway genes in mouse embryonic stem cells

High-throughput gene trapping is a random approach for inducing insertional mutations across the mouse genome. This approach uses gene trap vectors that simultaneously inactivate and report the expression of the trapped gene at the insertion site, and provide a DNA tag for the rapid identification o...

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Autors principals: De-Zolt, Silke, Schnütgen, Frank, Seisenberger, Claudia, Hansen, Jens, Hollatz, Melanie, Floss, Thomas, Ruiz, Patricia, Wurst, Wolfgang, von Melchner, Harald
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369290/
https://ncbi.nlm.nih.gov/pubmed/16478711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnj026
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