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Mechanisms of genetic robustness in RNA viruses

Two key features of RNA viruses are their compacted genomes and their high mutation rate. Accordingly, deleterious mutations are common and have an enormous impact on viral fitness. In their multicellular hosts, robustness can be achieved by genomic redundancy, including gene duplication, diploidy,...

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Detalhes bibliográficos
Main Authors: Elena, Santiago F, Carrasco, Purificación, Daròs, José-Antonio, Sanjuán, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369264/
https://ncbi.nlm.nih.gov/pubmed/16452927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400636
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