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Repression of polymerase I-mediated gene expression at Trypanosoma brucei telomeres

The African trypanosome, Trypanosoma brucei, is a flagellated pathogenic protozoan that branched early from the eukaryotic lineage. Unusually, it uses RNA polymerase I (Pol I) for mono-telomeric expression of variant surface glycoprotein (VSG) genes in bloodstream-form cells. Many other subtelomeric...

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Bibliographic Details
Main Authors: Glover, Lucy, Horn, David
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369228/
https://ncbi.nlm.nih.gov/pubmed/16311518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400575
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