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ARE-mRNA degradation requires the 5′–3′ decay pathway
As an important mode of suppressing gene expression, messenger RNAs containing an AU-rich element (ARE) in the 3′ untranslated region are rapidly degraded in the cytoplasm. ARE-mediated mRNA decay (AMD) is initiated by deadenylation, and in vitro studies have indicated that subsequent degradation oc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369226/ https://ncbi.nlm.nih.gov/pubmed/16299471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400572 |
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