Numb and α-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs

During asymmetric cell division in Drosophila sensory organ precursors (SOPs), the Numb protein segregates into one of the two daughter cells, in which it inhibits Notch signalling to specify pIIb cell fate. We show here that Numb acts in SOP cells by inducing the endocytosis of Sanpodo, a four-pass...

Full description

Saved in:
Bibliographic Details
Main Authors: Hutterer, Andrea, Knoblich, Juergen A
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Scientific Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369167/
https://ncbi.nlm.nih.gov/pubmed/16113648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400500
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items