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Numb and α-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs
During asymmetric cell division in Drosophila sensory organ precursors (SOPs), the Numb protein segregates into one of the two daughter cells, in which it inhibits Notch signalling to specify pIIb cell fate. We show here that Numb acts in SOP cells by inducing the endocytosis of Sanpodo, a four-pass...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369167/ https://ncbi.nlm.nih.gov/pubmed/16113648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400500 |
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