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Numb and α-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs

During asymmetric cell division in Drosophila sensory organ precursors (SOPs), the Numb protein segregates into one of the two daughter cells, in which it inhibits Notch signalling to specify pIIb cell fate. We show here that Numb acts in SOP cells by inducing the endocytosis of Sanpodo, a four-pass...

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Hlavní autoři: Hutterer, Andrea, Knoblich, Juergen A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369167/
https://ncbi.nlm.nih.gov/pubmed/16113648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400500
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