Wordt geladen...

Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation

The ubiquitin ligase Cbl mediates ubiquitination of activated receptor tyrosine kinases (RTKs) and interacts with endocytic scaffold complexes, including CIN85/endophilins, to facilitate RTK endocytosis and degradation. Several mechanisms regulate the functions of Cbl to ensure the fine-tuning of RT...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Haglund, Kaisa, Schmidt, Mirko H H, Wong, Esther Sook Miin, Guy, Graeme R, Dikic, Ivan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369112/
https://ncbi.nlm.nih.gov/pubmed/15962011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400453
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!