Borna Disease Virus Accelerates Inflammation and Disease Associated with Transgenic Expression of Interleukin-12 in the Central Nervous System

Targeted expression of biologically active interleukin-12 (IL-12) in astrocytes of the central nervous system (CNS) results in spontaneous neuroimmunological disease of aged mice. Borna disease virus (BDV) can readily multiply in the mouse CNS but does not trigger disease in most strains. Here we sh...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Freude, Susanna, Hausmann, Jürgen, Hofer, Markus, Pham-Mitchell, Ngan, Campbell, Iain L., Staeheli, Peter, Pagenstecher, Axel
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Pathogenesis and Immunity
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12414961/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.23.12223-12232.2002
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