Borna Disease Virus Accelerates Inflammation and Disease Associated with Transgenic Expression of Interleukin-12 in the Central Nervous System

Targeted expression of biologically active interleukin-12 (IL-12) in astrocytes of the central nervous system (CNS) results in spontaneous neuroimmunological disease of aged mice. Borna disease virus (BDV) can readily multiply in the mouse CNS but does not trigger disease in most strains. Here we sh...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Freude, Susanna, Hausmann, Jürgen, Hofer, Markus, Pham-Mitchell, Ngan, Campbell, Iain L., Staeheli, Peter, Pagenstecher, Axel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2002
Gaiak:
Pathogenesis and Immunity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC136910/
https://ncbi.nlm.nih.gov/pubmed/12414961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.23.12223-12232.2002
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