Inhibition of Hepatitis Delta Virus RNA Editing by Short Inhibitory RNA-Mediated Knockdown of ADAR1 but Not ADAR2 Expression

Hepatitis delta virus (HDV) requires host RNA editing at the viral RNA amber/W site. Of the two host genes responsible for RNA editing via deamination of adenosines in double-stranded RNAs, short inhibitory RNA-mediated knockdown of host ADAR1 expression but not that of ADAR2 led to decreased HDV am...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Jayan, Geetha C., Casey, John L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Replication
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136899/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12414985/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.23.12399-12404.2002
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