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Inhibition of Hepatitis Delta Virus RNA Editing by Short Inhibitory RNA-Mediated Knockdown of ADAR1 but Not ADAR2 Expression

Hepatitis delta virus (HDV) requires host RNA editing at the viral RNA amber/W site. Of the two host genes responsible for RNA editing via deamination of adenosines in double-stranded RNAs, short inhibitory RNA-mediated knockdown of host ADAR1 expression but not that of ADAR2 led to decreased HDV am...

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Detalhes bibliográficos
Main Authors: Jayan, Geetha C., Casey, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136899/
https://ncbi.nlm.nih.gov/pubmed/12414985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.23.12399-12404.2002
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