Mucosal Immunization with Live Recombinant Bovine Respiratory Syncytial Virus (BRSV) and Recombinant BRSV Lacking the Envelope Glycoprotein G Protects against Challenge with Wild-Type BRSV

Recombinant bovine respiratory syncytial virus (rBRSV) and an rBRSV deletion mutant lacking the G gene (rBRSVΔG) were characterized in calves with respect to replication competence, attenuation, and protective efficacy as live-attenuated BRSV vaccines. Both recombinant viruses were safe and induced...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Schmidt, Ulrike, Beyer, Jörg, Polster, Ulf, Gershwin, Laurel J., Buchholz, Ursula J.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Vaccines and Antiviral Agents
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136874/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12414977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.23.12355-12359.2002
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