Mapping of Functional Regions in the Amino-Terminal Portion of the Herpes Simplex Virus ICP27 Regulatory Protein: Importance of the Leucine-Rich Nuclear Export Signal and RGG Box RNA-Binding Domain

Infected-cell protein 27 (ICP27) is an essential herpes simplex virus type 1 (HSV-1) regulatory protein that activates a subset of viral delayed-early and late genes, at least in part through posttranscriptional mechanisms. Previous studies have shown that the amino (N)-terminal half of the protein...

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Autores principales: Lengyel, Joy, Guy, Chandra, Leong, Vivian, Borge, Sarah, Rice, Stephen A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC136872/
https://ncbi.nlm.nih.gov/pubmed/12414929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.23.11866-11879.2002
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