Effect of RG 12525, an oral leukotriene D4 antagonist, on the airway response to inhaled leukotriene D4 in subjects with mild asthma.

We have studied the effect of RG 12525, an oral leukotriene D4 (LTD4) antagonist, on LTD4-induced bronchoconstriction in eight male subjects with mild asthma (baseline FEV1 greater than 80% predicted) in a double-blind, placebo-controlled fashion. RG 12525 800 mg displaced the dose-response curve fo...

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Detalles Bibliográficos
Main Authors: Wahedna, I, Wisniewski, A S, Tattersfield, A E
Formato: Artigo
Idioma:Inglês
Publicado: 1991
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368616/
https://ncbi.nlm.nih.gov/pubmed/1958449
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