Critical Role for Perforin-, Fas/FasL-, and TNFR1-Mediated Cytotoxic Pathways in Down-Regulation of Antigen-Specific T Cells during Persistent Viral Infection

Viral persistence following infection with invasive strains of lymphocytic choriomeningitis virus (LCMV) can be achieved by selective down-regulation of virus-specific T lymphocytes. High viral burden in the onset of infection drives responding cells into functional unresponsiveness (anergy) that ca...

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Pubblicato in:	J Virol
Autori principali:	Zhou, Shenghua, Ou, Rong, Huang, Lei, Moskophidis, Demetrius
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11752172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.2.829-840.2002
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