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An investigation of the role of metabolism in dapsone-induced methaemoglobinaemia using a two compartment in vitro test system.

1. We have utilized a two compartment system in which two teflon chambers are separated by a semi-permeable membrane in order to investigate the role of metabolism in dapsone-induced methaemoglobinaemia. Compartment A contained a drug metabolizing system (microsomes prepared from human liver +/- NAD...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tingle, M D, Coleman, M D, Park, B K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368303/
https://ncbi.nlm.nih.gov/pubmed/2288829
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