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Safety and Immunogenicity in Neonatal Mice of a Hyperattenuated Listeria Vaccine Directed against Human Immunodeficiency Virus

CD8(+) T cells are a major component of the adaptive response of a host to infections by viruses and other intracellular pathogenic agents. However, because of the intrinsic immaturity of the immune system of neonatal animals, neonates are highly sensitive to a variety of pathogens and may be unable...

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Autori principali: Rayevskaya, Marina, Kushnir, Natasha, Frankel, Fred R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC136818/
https://ncbi.nlm.nih.gov/pubmed/11752181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.918-922.2002
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