A Variable Region 3 (V3) Mutation Determines a Global Neutralization Phenotype and CD4-Independent Infectivity of a Human Immunodeficiency Virus Type 1 Envelope Associated with a Broadly Cross-Reactive, Primary Virus-Neutralizing Antibody Response

The human serum human immunodeficiency virus type 1 (HIV-1)-neutralizing serum 2 (HNS2) neutralizes many primary isolates of different clades of HIV-1, and virus expressing envelope from the same donor, clone R2, is neutralized cross-reactively by HIV-immune human sera. The basis for this cross-reac...

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Detalhes bibliográficos
Main Authors: Zhang, Peng Fei, Bouma, Peter, Park, Eun Ju, Margolick, Joseph B., Robinson, James E., Zolla-Pazner, Susan, Flora, Michael N., Quinnan, Gerald V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136808/
https://ncbi.nlm.nih.gov/pubmed/11752155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.644-655.2002
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