Evidence for Human Immunodeficiency Virus Type 1 Replication In Vivo in CD14(+) Monocytes and Its Potential Role as a Source of Virus in Patients on Highly Active Antiretroviral Therapy

In vitro studies show that human immunodeficiency virus type 1 (HIV-1) does not replicate in freshly isolated monocytes unless monocytes differentiate to monocyte-derived macrophages. Similarly, HIV-1 may replicate in macrophages in vivo, whereas it is unclear whether blood monocytes are permissive...

Полное описание

Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Zhu, Tuofu, Muthui, David, Holte, Sarah, Nickle, David, Feng, Feng, Brodie, Scott, Hwangbo, Yon, Mullins, James I., Corey, Lawrence
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2002
Предметы:	Pathogenesis and Immunity
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136806/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11752161/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.2.707-716.2002
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