Immune-Mediated Positive Selection Drives Human Immunodeficiency Virus Type 1 Molecular Variation and Predicts Disease Duration

Using likelihood-based evolutionary methods, we demonstrate that the broad genetic diversity of human immunodeficiency virus type 1 (HIV-1) in an infected individual is a consequence of site-specific positive selection for diversity, a likely consequence of immune recognition. In particular, the ext...

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Εκδόθηκε σε:	J Virol
Κύριοι συγγραφείς:	Ross, Howard A., Rodrigo, Allen G.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 2002
Θέματα:	Recombination and Evolution
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12388731/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.22.11715-11720.2002
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