Immune-Mediated Positive Selection Drives Human Immunodeficiency Virus Type 1 Molecular Variation and Predicts Disease Duration
Using likelihood-based evolutionary methods, we demonstrate that the broad genetic diversity of human immunodeficiency virus type 1 (HIV-1) in an infected individual is a consequence of site-specific positive selection for diversity, a likely consequence of immune recognition. In particular, the ext...
محفوظ في:
| الحاوية / القاعدة: | J Virol |
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| المؤلفون الرئيسيون: | , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
2002
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12388731/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.22.11715-11720.2002 |
| الوسوم: |
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