Elevated Levels of Tumor Necrosis Factor Alpha (TNF-α) in Human Immunodeficiency Virus Type 1-Transgenic Mice: Prevention of Death by Antibody to TNF-α

Homozygous human immunodeficiency virus type 1 (HIV-1)-transgenic mice (Tg26) appear normal at birth but die within 3 to 4 weeks. The skin of these animals shows diffuse scaling and high-level expression of both HIV-1 mRNA and gp120. Previous experiments showed that treatment with human chorionic go...

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Hlavní autoři: De, Swapan K., Devadas, Krishnakumar, Notkins, Abner Louis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136749/
https://ncbi.nlm.nih.gov/pubmed/12388730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11710-11714.2002
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