Comparison of the Complete DNA Sequences of the Oka Varicella Vaccine and Its Parental Virus

The DNA sequences of the Oka varicella vaccine virus (V-Oka) and its parental virus (P-Oka) were completed. Comparison of the sequences revealed 42 base substitutions, which led to 20 amino acid conversions and length differences in tandem repeat regions (R1, R3, and R4) and in an origin of DNA repl...

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Bibliographic Details
Main Authors: Gomi, Yasuyuki, Sunamachi, Hiroki, Mori, Yasuko, Nagaike, Kazuhiro, Takahashi, Michiaki, Yamanishi, Koichi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136748/
https://ncbi.nlm.nih.gov/pubmed/12388706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11447-11459.2002
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