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Reversible Binding of Recombinant Human Immunodeficiency Virus Type 1 Gag Protein to Nucleic Acids in Virus-Like Particle Assembly In Vitro

Recombinant human immunodeficiency virus type 1 (HIV-1) Gag protein can assemble into virus-like particles (VLPs) in suitable buffer conditions with nucleic acid. We have explored the role of nucleic acid in this assembly process. HIV-1 nucleocapsid protein, a domain of Gag, can bind to oligodeoxynu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Feng, Ya-Xiong, Li, Tong, Campbell, Stephen, Rein, Alan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136742/
https://ncbi.nlm.nih.gov/pubmed/12388738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11757-11762.2002
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