Proline Residues within Spacer Peptide p1 Are Important for Human Immunodeficiency Virus Type 1 Infectivity, Protein Processing, and Genomic RNA Dimer Stability

The full-length human immunodeficiency virus type 1 (HIV-1) mRNA encodes two precursor polyproteins, Gag and GagProPol. An infrequent ribosomal frameshifting event allows these proteins to be synthesized from the same mRNA in a predetermined ratio of 20 Gag proteins for each GagProPol. The RNA frame...

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Detalhes bibliográficos
Main Authors: Hill, Melissa K., Shehu-Xhilaga, Miranda, Crowe, Suzanne M., Mak, Johnson
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136739/
https://ncbi.nlm.nih.gov/pubmed/12388684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11245-11253.2002
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