Multimeric Soluble CD40 Ligand and GITR Ligand as Adjuvants for Human Immunodeficiency Virus DNA Vaccines

For use in humans, human immunodeficiency virus (HIV) DNA vaccines may need to include immunostimulatory adjuvant molecules. CD40 ligand (CD40L), a member of the tumor necrosis factor (TNF) superfamily (TNFSF), is one candidate adjuvant, but it has been difficult to use because it is normally expres...

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Autores principales: Stone, Geoffrey W., Barzee, Suzanne, Snarsky, Victoria, Kee, Kristin, Spina, Celsa A., Yu, Xiao-Fang, Kornbluth, Richard S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367159/
https://ncbi.nlm.nih.gov/pubmed/16439533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1762-1772.2006
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