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Hyperphosphorylation of the Rotavirus NSP5 Protein Is Independent of Serine 67 or NSP2, and the Intrinsic Insolubility of NSP5 Is Regulated by Cellular Phosphatases

The NSP5 protein is required for viroplasm formation during rotavirus infection and is hyperphosphorylated into 32- to 35-kDa isoforms. Earlier studies reported that NSP5 is not hyperphosphorylated without NSP2 coexpression or deleting the NSP5 N terminus and that serine 67 is essential for NSP5 hyp...

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Bibliografische gegevens
Hoofdauteurs: Sen, Adrish, Agresti, Darin, Mackow, Erich R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367154/
https://ncbi.nlm.nih.gov/pubmed/16439537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1807-1816.2006
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