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Conversion of a Porin-like Peptide Channel into a Gramicidin-like Channel by Glycine to D-alanine Substitutions
The β-barrel and β-helix formation, as in porins and gramicidin, respectively, represent two distinct mechanisms for ion channel formation by β-sheet proteins in membranes. The design of β-barrel proteins is difficult due to incomplete understanding of the basic principles of folding. The design of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367119/ https://ncbi.nlm.nih.gov/pubmed/16272445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072751 |
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