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A Competitive Kinetic Model of Nucleic Acid Surface Hybridization in the Presence of Point Mutants

Microarray analysis has become increasingly complex due to the growing size of arrays and the inherent cross-binding of targets. In this work, we explore the effects of matched and mismatched target species concentrations, temperature, and the time of hybridization on sensing specificity in two-comp...

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Main Authors: Bishop, J., Blair, S., Chagovetz, A. M.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367108/
https://ncbi.nlm.nih.gov/pubmed/16284267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072314
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