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A Competitive Kinetic Model of Nucleic Acid Surface Hybridization in the Presence of Point Mutants
Microarray analysis has become increasingly complex due to the growing size of arrays and the inherent cross-binding of targets. In this work, we explore the effects of matched and mismatched target species concentrations, temperature, and the time of hybridization on sensing specificity in two-comp...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367108/ https://ncbi.nlm.nih.gov/pubmed/16284267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072314 |
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