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A Competitive Kinetic Model of Nucleic Acid Surface Hybridization in the Presence of Point Mutants

Microarray analysis has become increasingly complex due to the growing size of arrays and the inherent cross-binding of targets. In this work, we explore the effects of matched and mismatched target species concentrations, temperature, and the time of hybridization on sensing specificity in two-comp...

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Main Authors: Bishop, J., Blair, S., Chagovetz, A. M.
格式: Artigo
語言:Inglês
出版: Biophysical Society 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367108/
https://ncbi.nlm.nih.gov/pubmed/16284267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072314
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