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Prediction of Hybridization and Melting for Double-Stranded Nucleic Acids

This article presents a general statistical mechanical approach to describe self-folding together with the hybridization between a pair of finite length DNA or RNA molecules. The model takes into account the entire ensemble of single- and double-stranded species in solution and their mole fractions...

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Detalhes bibliográficos
Main Authors: Dimitrov, Roumen A., Zuker, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304344/
https://ncbi.nlm.nih.gov/pubmed/15240459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.020743
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