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Is the Mechanical Activity of Epithelial Cells Controlled by Deformations or Forces?

The traction forces developed by cells depend strongly on the substrate rigidity. In this letter, we characterize quantitatively this effect on MDCK epithelial cells by using a microfabricated force sensor consisting in a high-density array of soft pillars whose stiffness can be tailored by changing...

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Hlavní autoři: Saez, Alexandre, Buguin, Axel, Silberzan, Pascal, Ladoux, Benoît
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367004/
https://ncbi.nlm.nih.gov/pubmed/16214867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.071217
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