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Is the Mechanical Activity of Epithelial Cells Controlled by Deformations or Forces?

The traction forces developed by cells depend strongly on the substrate rigidity. In this letter, we characterize quantitatively this effect on MDCK epithelial cells by using a microfabricated force sensor consisting in a high-density array of soft pillars whose stiffness can be tailored by changing...

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Detalhes bibliográficos
Main Authors: Saez, Alexandre, Buguin, Axel, Silberzan, Pascal, Ladoux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367004/
https://ncbi.nlm.nih.gov/pubmed/16214867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.071217
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