Human Immunodeficiency Virus Envelope (gp120) Binding to DC-SIGN and Primary Dendritic Cells Is Carbohydrate Dependent but Does Not Involve 2G12 or Cyanovirin Binding Sites: Implications for Structural Analyses of gp120-DC-SIGN Binding

The calcium-dependent lectin, DC-SIGN, binds to human immunodeficiency virus (HIV) (and simian immunodeficiency virus) gp120 and mediates the binding and transfer of HIV from monocyte-derived dendritic cells (MDDCs) to permissive T cells. However, it has been recently reported that DC-SIGN binding t...

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Pubblicato in:	J Virol
Autori principali:	Hong, Patrick W.-P., Flummerfelt, Karen B., de Parseval, Aymeric, Gurney, Kevin, Elder, John H., Lee, Benhur
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.24.12855-12865.2002
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