Human Immunodeficiency Virus Envelope (gp120) Binding to DC-SIGN and Primary Dendritic Cells Is Carbohydrate Dependent but Does Not Involve 2G12 or Cyanovirin Binding Sites: Implications for Structural Analyses of gp120-DC-SIGN Binding

The calcium-dependent lectin, DC-SIGN, binds to human immunodeficiency virus (HIV) (and simian immunodeficiency virus) gp120 and mediates the binding and transfer of HIV from monocyte-derived dendritic cells (MDDCs) to permissive T cells. However, it has been recently reported that DC-SIGN binding t...

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Détails bibliographiques
Auteurs principaux: Hong, Patrick W.-P., Flummerfelt, Karen B., de Parseval, Aymeric, Gurney, Kevin, Elder, John H., Lee, Benhur
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Replication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC136699/
https://ncbi.nlm.nih.gov/pubmed/12438611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12855-12865.2002
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