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Effects of Chlorpromazine on Mechanical Properties of the Outer Hair Cell Plasma Membrane

An optical tweezers system was used to characterize the effects of chlorpromazine (CPZ) on the mechanical properties of the mammalian outer hair cell (OHC) through the formation of plasma membrane tethers. Such tethers exhibited force relaxation when held at a constant length for several minutes. We...

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Main Authors: Murdock, David R., Ermilov, Sergey A., Spector, Alexander A., Popel, Aleksander S., Brownell, William E., Anvari, Bahman
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2005
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366974/
https://ncbi.nlm.nih.gov/pubmed/16199506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.069872
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