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Effects of Chlorpromazine on Mechanical Properties of the Outer Hair Cell Plasma Membrane

An optical tweezers system was used to characterize the effects of chlorpromazine (CPZ) on the mechanical properties of the mammalian outer hair cell (OHC) through the formation of plasma membrane tethers. Such tethers exhibited force relaxation when held at a constant length for several minutes. We...

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Detalhes bibliográficos
Main Authors: Murdock, David R., Ermilov, Sergey A., Spector, Alexander A., Popel, Aleksander S., Brownell, William E., Anvari, Bahman
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366974/
https://ncbi.nlm.nih.gov/pubmed/16199506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.069872
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