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Construction and Characterization of Adenovirus Serotype 5 Packaged by Serotype 3 Hexon

Adenovirus serotype 5 (Ad5) has great potential for gene therapy applications. A major limitation, however, is the host immune response against Ad5 infection that often prevents the readministration of Ad5 vectors. In this regard, the most abundant capsid protein, hexon, has been implicated as the m...

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Main Authors: Wu, Hongju, Dmitriev, Igor, Kashentseva, Elena, Seki, Toshiro, Wang, Minghui, Curiel, David T.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC136697/
https://ncbi.nlm.nih.gov/pubmed/12438602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12775-12782.2002
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