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Interfacial Tryptophan Residues: A Role for the Cation-π Effect?

Integral membrane proteins are characterized by having a preference for aromatic residues, e.g., tryptophan (W), at the interface between the lipid bilayer core and the aqueous phase. The reason for this is not clear, but it seems that the preference is related to a complex interplay between steric...

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Bibliografiske detaljer
Main Authors: Petersen, Frederic N. R., Jensen, Morten Ø., Nielsen, Claus H.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366964/
https://ncbi.nlm.nih.gov/pubmed/16150973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.061804
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