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Modeling Flexible Loops in the Dark-Adapted and Activated States of Rhodopsin, a Prototypical G-Protein-Coupled Receptor

Conformational possibilities of flexible loops in rhodopsin, a prototypical G-protein-coupled receptor, were studied by modeling both in the dark-adapted (R) and activated (R*) states. Loop structures were built onto templates representing the R and R* states of the TM region of rhodopsin developed...

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Detalhes bibliográficos
Main Authors: Nikiforovich, Gregory V., Marshall, Garland R.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366946/
https://ncbi.nlm.nih.gov/pubmed/16199504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.070722
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