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Effects of Receptor Clustering on Ligand Dissociation Kinetics: Theory and Simulations
Receptor-ligand binding is a critical first step in signal transduction and the duration of the interaction can impact signal generation. In mammalian cells, clustering of receptors may be facilitated by heterogeneous zones of lipids, known as lipid rafts. In vitro experiments show that disruption o...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Biophysical Society
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366939/ https://ncbi.nlm.nih.gov/pubmed/16150967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.065300 |
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