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In Vitro Activity of DX-619, a Novel Des-Fluoro(6) Quinolone, against a Panel of Streptococcus pneumoniae Mutants with Characterized Resistance Mechanisms
The in vitro activities of DX-619 and four other quinolones were compared against Streptococcus pneumoniae mutants that contained a variety of alterations within the quinolone resistance-determining regions. DX-619 was the most potent quinolone and was least affected by the mutations.
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366926/ https://ncbi.nlm.nih.gov/pubmed/16436749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.796-798.2006 |
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