Effect of Amphotericin B and Micafungin Combination on Survival, Histopathology, and Fungal Burden in Experimental Aspergillosis in the p47(phox)(−)(/)(−) Mouse Model of Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is an inherited disorder of the NADPH oxidase characterized by recurrent life-threatening bacterial and fungal infections. We characterized the effects of single and combination antifungal therapy on survival, histopathology, and laboratory markers of fungal burde...

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Detalhes bibliográficos
Main Authors: Dennis, Carly G., Greco, William R., Brun, Yseult, Youn, Richard, Slocum, Harry K., Bernacki, Ralph J., Lewis, Russell, Wiederhold, Nathan, Holland, Steven M., Petraitiene, Ruta, Walsh, Thomas J., Segal, Brahm H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366912/
https://ncbi.nlm.nih.gov/pubmed/16436692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.422-427.2006
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