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Neutrophil-Bead Collision Assay: Pharmacologically Induced Changes in Membrane Mechanics Regulate the PSGL-1/P-Selectin Adhesion Lifetime

Visualization of flowing neutrophils colliding with adherent 1-μm-diameter beads presenting P-selectin allowed the simultaneous measurement of collision efficiency (ɛ), membrane tethering fraction (f), membrane tether growth dynamics, and PSGL-1/P-selectin binding lifetime. For 1391 collisions analy...

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Bibliografiska uppgifter
Huvudupphovsmän: Edmondson, K. E., Denney, W. S., Diamond, S. L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Biophysical Society 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366853/
https://ncbi.nlm.nih.gov/pubmed/16100264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.066134
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