Requirements for De Novo Initiation of RNA Synthesis by Recombinant Flaviviral RNA-Dependent RNA Polymerases

RNA-dependent RNA polymerases (RdRps) that initiate RNA synthesis by a de novo mechanism should specifically recognize the template initiation nucleotide, T1, and the substrate initiation nucleotide, the NTPi. The RdRps from hepatitis C virus (HCV), bovine viral diarrhea virus (BVDV), and GB virus-B...

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Bibliographic Details
Main Authors: Ranjith-Kumar, C. T., Gutshall, Les, Kim, Min-Ju, Sarisky, Robert T., Kao, C. Cheng
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136677/
https://ncbi.nlm.nih.gov/pubmed/12438578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12526-12536.2002
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