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Terminal Nucleotidyl Transferase Activity of Recombinant Flaviviridae RNA-Dependent RNA Polymerases: Implication for Viral RNA Synthesis

Recombinant hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) was reported to possess terminal transferase (TNTase) activity, the ability to add nontemplated nucleotides to the 3′ end of viral RNAs. However, this TNTase was later purported to be a cellular enzyme copurifying with the HCV R...

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Hlavní autoři: Ranjith-Kumar, C. T., Gajewski, J., Gutshall, L., Maley, D., Sarisky, R. T., Kao, C. Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC115107/
https://ncbi.nlm.nih.gov/pubmed/11507207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8615-8623.2001
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