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Theoretical Studies of the M2 Transmembrane Segment of the Glycine Receptor: Models of the Open Pore Structure and Current-Voltage Characteristics

The pentameric glycine receptor (GlyR), a member of the nicotinicoid superfamily of ligand-gated ion channels, is an inhibitory Cl(−) channel that is gated by glycine. Using recently published NMR data of the second transmembrane segment (M2) of the human α1 GlyR, structural models of pentameric ass...

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Autors principals: Cheng, Mary Hongying, Cascio, Michael, Coalson, Rob D.
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366671/
https://ncbi.nlm.nih.gov/pubmed/15951389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.060368
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